The Journal of Immunology published a research paper entitled "Betaine Ameliorates Experimental Autoimmune Encephalomyelitis by Inhibiting Dendritic Cell Derived-IL-6 Production and Th17 Differentiation" by Professor Du Changsheng, School of Life Science and Technology, Tongji University. In this study, we constructed a mouse model of multiple sclerosis and found that Betaine/Beet extract can effectively alleviate the clinical symptoms of EAE mice.
Amazing nature contains rich treasures. Betaine, as a quaternary ammonium compound of amphoteric ions, was first found in beet in the 19th century, and later in microorganisms, plants and animals, especially in wheat, shellfish, spinach and shrimp. Betaine's primary physiological function is to regulate osmotic pressure and act as a methyl donor. In addition, Betaine has been used as a natural feed additive for more than 50 years. However, it is not clear whether Betaine has a certain therapeutic effect on MS.
Recent studies have shown that Betaine can alleviate MS pathology by inhibiting DC/IL-6 secretion and Th17 differentiation.